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Research: Stem cells are transformed into eggs

The announcement this week about a ground-breaking experiment in which stem cells from ovaries were made into eggs has led to provocative predictions for helping fertility patients. Fertility expert and best-selling author Dr. Robert Greene shares his analysis of the new research.
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Feb 29, 2012
Dr. Robert Greene
Photo by: Courtesy of Dr. Robert Greene

One of the most vexing problems in human reproduction has been the accepted fact that women are born with every egg that they are ever going to have. As women age, the number of viable eggs goes down until she is no longer able to conceive her own biological child. A new study has questioned this current position by actually creating new eggs from stem cells.

Stem cells are the special cells within the body that have not been assigned a specific identity. As a result, they can become kidney cells or skin cells or muscle cells. But until now, there has not been confirmation that they can become the special cells that are necessary to support reproduction (eggs or sperm). This new study has changed that perspective.

It is important to point out that this is the first report and therefore the technique needs to be repeated and verified before we can be certain of this new breakthrough. It is also noteworthy that this study involved a process where women were having their ovaries removed as part of gender re-assignment surgery. The ovaries were then processed in the lab in order to derive the cells that reportedly produced a limited number of eggs. It is therefore possible that even if this study is confirmed that it will only apply to young women and that the technique would require that they lose an ovary in order to create these eggs. Since it is older women that typically need to generate new eggs, we aren’t yet certain that this new breakthrough will ever be of practical value to women most in need of these results. Nonetheless, each step toward overcoming a potential barrier to reproduction is cause for celebration—even if we simply develop new information that assists us in understanding other aspects of reproduction.

What do you think of the news that doctors may be able to create eggs using a woman's stem cells?

Robert Greene, M.D., FACOG, is a physician at the CNY Fertility Center in central New York and the author of Perfect Hormone Balance for Fertility, Perfect Hormone Balance for Pregnancy, and Happy Baby, Healthy Mom Pregnancy Journal. You can read Dr. Greene's blog, The Greene Guide, and follow him on Twitter. This post was first published on Dr. Greene's blog, and he kindly shared it with ConceiveOnline.com.

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